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The CISD1 protein and CISD2 protein, which are present in mitochondria and the endoplasmic reticulum (ER), inhibit ferroptosis by reducing iron uptake from mitochondria and ROS production, respectively [57, 58]

(PubMed) Mei Z, Cogswell ME, Looker AC, et al

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This exposure results in the creation of aqueous pores within the lamellar lipid regions of the SC, thereby facilitating the drug diffusion across the skin barrier [192, 244]

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A recent study revealed a distinct cell typespecific KD response in the brain: metabolic plasticity is found in astrocytes and neurons, but not in oligodendrocytes (129), which highlights the importance of narrowing the variation in KD responses